Canal parvovirus disease is a strong infectious disease with high contact sexual contagion in dogs. Clinically, acute hemorrhagic enteritis and myocarditis are characterized.
【Symptoms】
Dogs infected by parvovirus can be clinically divided into enteritis type and myocarditis type. The incubation period of natural infection of enteritis type
natural infection is 4-14 days, and the disease begins to show fever (above 40℃), depression, no food, and vomiting. In the early stage, vomit is food, that is, mucus, yellow-green or blood-related. Diarrhea began to occur about one day. At the beginning of the disease, the feces are thin, and as the disease develops, the feces are bloody stools with brown or tomato sauce. The number of times increases in the future, the internal pressure becomes severe, and the bloody stool will have a special fishy smell. After a few hours of bleeding stool, the sick dog showed severe dehydration symptoms, with sunken eyes, dry nose, decreased skin elasticity and significant weight loss. For cases of severe intestinal bleeding, the corruption of the intestinal content can cause endotoxin poisoning and disseminated intravascular coagulation, causing the body to fall into shock and coma. With blood changes, the number of white blood cells in a sick dog can be as low as 0. At this time, the majority of dogs die. If the number of rod-shaped neutrophils gradually increases, it will gradually improve.
myocarditis type
is more common in dogs around 40 days old, and the avatar symptoms of sick dogs are not obvious. Some suddenly have difficulty breathing, heart failure, and die in a short period of time; some dogs can be seen to die after mild diarrhea.
【Prevention】
If this disease is found, it should be isolated and raised immediately. Prevent sick dogs and sick dog breeders from contacting healthy dogs, and repeatedly disinfect the kennels and venues with 2% alkaline water or 10-20% bleach. 84 and DuPont-Weico are both effective disinfectants. Single seedlings of canine parvovirus enteritis are rare and are mostly combined with other viral infectious diseases, so the immune program is the same as the canine distemper vaccine.
【Treatment】
(1) Canine parvovirus disease is treated with canine parvovirus monoclonal antibodies or high-free serum. In addition, it is also ideal to use drugs such as interferon alpha or Julipeptide and immunoglobulin. At present, there are manufacturers in my country that have certain therapeutic effects in clinical applications.
(2) Symptomatic treatment: rehydration therapy, add 5% sodium bicarbonate injection to intravenous injection with isotonic glucose saline. The amount of fluid replenishment can be determined based on the degree of dehydration.
(3) Anti-inflammatory, hemostasis, antiemetic, gentamicin 10,000 units/kg body weight, intramuscular injection, or 50,000 units/kg body weight mixed with kanamycin 50,000 units/kg body weight. Vitamin K11 mg/kg body weight, Vk30.4 mg/kg body weight, mixed intramuscular injection. Gastroenteramide 2 mg/kg body weight.
(4) Usually, dexamethasone should not be used for the treatment of parvovirus. It can cause severe blood loss.
(5) Guohao Hi-Tech treatment plan: Dogshule + interferon + cephalosporin are used in combination, and they are used for 1-2 days in a row.